Dear MARMAM subscribers, We are pleased to announce the publication of our paper in "Environmental pollution": Investigation of silver (Ag) deposition in tissues from stranded cetaceans by autometallography (AMG) Wen-Ta Li, Hui-Wen Chang, Meng-Hsien Chen, Hue-Ying Chiou, Bang-Yeh Liou, Victor Fei Pang, Wei-Cheng Yang, Chian-Ren Jeng https://doi.org/10.1016/j.envpol.2018.01.010 Highlights •Ag distributions in liver and kidney tissues of cetaceans are demonstrated by AMG. •Ag concentrations in liver and kidney tissues of cetaceans are estimated by CHAA. •Cetaceans have a different metabolic profile of Ag. •Ag contamination in Pacific Ocean is more severe than other marine regions. •The health of cetacean in Pacific Ocean may be negatively affected by Ag. Abstract Silver, such as silver nanoparticles (AgNPs), has been widely used in commercial products and may be released into the environment. The interaction between Ag deposition and biological systems is raising serious concerns because of one health consideration. Cetaceans, as the top predators of the oceans, may be exposed to Ag/Ag compounds and suffer negative health impacts from the deposition of these compounds in their bodies. In the present study, we utilized autometallography (AMG) to localize the Ag in the liver and kidney tissues of cetaceans and developed a model called the cetacean histological Ag assay (CHAA) to estimate the Ag concentrations in the liver and kidney tissues of cetaceans. Our results revealed that Ag was mainly located in hepatocytes, Kupffer cells and the epithelial cells of some proximal renal tubules. The tissue pattern of Ag/Ag compounds deposition in cetaceans was different from those in previous studies conducted on laboratory rats. This difference may suggest that cetaceans have a different metabolic profile of Ag, so a presumptive metabolic pathway of Ag in cetaceans is advanced. Furthermore, our results suggest that the Ag contamination in cetaceans living in the North-western Pacific Ocean is more severe than that in cetaceans living in other marine regions of the world. The level of Ag deposition in cetaceans living in the former area may have caused negative impacts on their health condition. Further investigations are warranted to study the systemic Ag distribution, the cause of death/stranding, and the infectious diseases in stranded cetaceans with different Ag concentrations for comprehensively evaluating the negative health effects caused by Ag in cetaceans. Free access to the article is available at (here <https://www.sciencedirect.com/science/article/pii/S0269749117344615>) until February 28, 2018. in addition, the full article can be requested at heerolee1104@gmail.com or via researchgate (here <https://www.researchgate.net/publication/322267197_Investigation_of_silver_Ag_deposition_in_tissues_from_stranded_cetaceans_by_autometallography_AMG?ev=prf_ov_fet_res&_iepl%5BviewId%5D=iOS8PYnPbMUMRQAXPDY94OZMiQjd71uvkp3m&_iepl%5Bcontexts%5D%5B0%5D=prfhpi&_iepl%5Bdata%5D%5BstandardItemCount%5D=2&_iepl%5Bdata%5D%5BuserSelectedItemCount%5D=0&_iepl%5Bdata%5D%5BtopHighlightCount%5D=1&_iepl%5Bdata%5D%5BtopHighlightIndex%5D=1&_iepl%5Bdata%5D%5BfeaturedItem1of1%5D=1&_iepl%5BtargetEntityId%5D=PB%3A322267197&_iepl%5BinteractionType%5D=publicationTitle> ) Best regards, Wen-Ta -- Wen-Ta Li, DVM, MS PhD candidate/Veterinary Pathologist Graduate Institute of Molecular and Comparative Pathobiology, School of Veterinary Medicine, National Taiwan University Veterinarian/Director, Taiwan Cetacean Society